hCG
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hCG (Human Chorionic Gonadotropin) is a heterodimeric glycoprotein hormone used in research as a high-affinity agonist of the LH/CG receptor (LHCGR) to study gonadotropin receptor pharmacology, cAMP-linked signaling, and steroidogenesis-related pathway outputs.
Research class: Glycoprotein hormone (α/β heterodimer)
Subunit composition: α-subunit ~92 aa + β-subunit ~145 aa (β is the unique CG subunit)
Approx. molecular mass: ~36.7 kDa (glycosylation-dependent)
CAS (intact hCG preparation): 9002-61-3
Deprecated CAS (seen in some catalogs): 11130-48-6, 53321-48-5
UNII: 20ED16GHEB
Common research endpoints: LHCGR binding/activation, cAMP/PKA pathway readouts, steroidogenic gene-expression markers, and receptor desensitization/internalization metrics
For research use only. Not for therapeutic or diagnostic applications.
Product is Pharama Grade
Name: Human chorionic gonadotropin (hCG)
CAS: 9002-61-3
UNII: 20ED16GHEB
Type: Heterodimeric glycoprotein hormone (α/β complex)
Subunits / Size
α-subunit: 92 amino acids
β-subunit: ~145 amino acids
Molecular mass: ~36–38 kDa (varies with glycosylation)
Glycosylation (key sites)
N-linked: α Asn52/Asn78; β Asn13/Asn30
O-linked (β CTP region): Ser121/Ser127/Ser132/Ser138
Research target
Receptor: LHCGR (LH/CG receptor)
Common readouts: receptor activation/binding and cAMP-linked signaling markers
For research use only. Not for therapeutic or diagnostic applications.
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